With the growth of e-commerce and rising health consciousness, the way in which con-sumers perceive advertising elements and form attitudes regarding food supplements has profoundly changed. This study builds on an understanding of food supplements, taking unique e-commerce settings and regulatory guidelines governing advertising practices into account. Drawing upon a modified Elaboration Likelihood Model by Cyr et al. (2018), this research adapts the model even further to examine how central- and pe-ripheral-processed advertising elements influence changes in attitude on a product de-tail page, in the food supplement context. A quantitative study was conducted to analyze consumers’ possible “Attitude Change” to a fictitious product detail page. The textual content (product descriptions, health claims, relating to "Health Claim Quality"), visual design (product pictures in different settings relating to "Product Visualization"), social components (recommendations, trust elements and reviews relating to "Connected-ness") and testimonials (pictures with testimonial persons relating to "Testimonials"), from three Austrian supplement market leaders were combined and presented to the participants in a separate layout, which based visually and structurally on the existing product detail pages. The anticipated attitude change among consumers did not reach statistical significance. However, the empirical findings support the conclusion that “At-titude Change” through advertising elements on a product detail page selling food sup-plements is primarily influenced by social identification (“Connectedness”), while “Health Claim Quality” and “Product Visualization” play a supportive role, that is not as influential, among other unexplored factors in this context. “Testimonials”, do not seem to have a direct effect on “Attitude Change”. The findings of this study indicate that product detail page elements that establish an emotional connection to the brand or product are especially effective in influencing consumers in their sustainable opinion formation.